Blackpool B.| 12 | | Hilton Park | | > | | Sat | 29 Aug 1959 | Salford | 45 | Liverpool C. | 8 | | The Willows | | > |
| Sat | 29 Aug 1959 | Swinton | 9 | St Helens | 17 | | Station Road | | > |
| Sat | 29 Aug 1959 | Whitehaven | 23 | Oldham | 5 | | Recreation Gnd | | > |
| Sat | 29 Aug 1959 | Widnes | 21 | Barrow | 15 | | Naughton | | > |
| Sat | 29 Aug 1959 | Wigan | 39 | Rochdale H. | 20 | | Central Park | | > |
| Sat | 29 Aug 1959 | Workington | 12 | Warrington | 33 | | Derwent Park | | > |
| Thu | 03 Sep 1959 | Blackpool B. | 7 | Leigh | 13 | | St Anne's Road | | > |
| Lancashire Cup - Round 2
|
|---|
| Mon | 07 Sep 1959 | Wigan | 39 | Salford | 15 | | Central Park | | > |
| Wed | 09 Sep 1959 | Leigh | 2 | Warrington | 27 | | Hilton Park | | > |
| Wed | 09 Sep 1959 | Widnes | 9 | St Helens | 24 | | Naughton | | > |
| Lancashire Cup - Semi Final
|
|---|
| Tue | 15 Sep 1959 | Wigan | 13 | Warrington | 15 | | Central Park | | > |
| Tue | 29 Sep 1959 | Whitehaven | 2 | St Helens | 18 | | Recreation Gnd | | > |
| Lancashire Cup - Final
|
|---|
| Sat | 31 Oct 1959 | Warrington | 5 | St Helens | 4 | | Central Park | 39,237 | > |