Altrincham| 3 | | [unknown] | | > | | Sat | 02 Mar 1901 | Barrow | 11 | Brighouse Rangers | 0 | | Cavendish Park | | > |
| Sat | 02 Mar 1901 | Birkenhead | 2 | Millom | 0 | | Park Station | | > |
| Sat | 02 Mar 1901 | Bradford | 7 | Swinton | 2 | | Park Avenue | | > |
| Sat | 02 Mar 1901 | Broughton R. | 24 | Tyldesley | 3 | | Wheater's | | > |
| Sat | 02 Mar 1901 | Dewsbury | 9 | Featherstone | 5 | | Crown Flatt | | > |
| Sat | 02 Mar 1901 | Goole | 2 | St Helens | 12 | | Victoria Grounds | | > |
| Sat | 02 Mar 1901 | Hebden Bridge | 6 | Whitworth | 0 | | [unknown] | | > |
| Sat | 02 Mar 1901 | Heckmondwike | 8 | Seaton Rangers | 0 | | Beck Lane | | > |
| Sat | 02 Mar 1901 | Huddersfield | 6 | Hull | 3 | | Fartown | | > |
| Sat | 02 Mar 1901 | Hull KR | 4 | Salford | 0 | | Craven Street | | > |
| Sat | 02 Mar 1901 | Hunslet | 8 | Wath Brow Hornets | 0 | | Parkside | | > |
| Sat | 02 Mar 1901 | Keighley | 13 | Kinsley | 0 | | Lawkholme Lane | | > |
| Sat | 02 Mar 1901 | Lancaster | 3 | Maryport | 3 | | Quay Meadow | | > |
| Sat | 02 Mar 1901 | Leeds Parish Church | 11 | Radcliffe | 0 | | Clarence Field | | > |
| Sat | 02 Mar 1901 | Leeds | 0 | Warrington | 19 | | Headingley | | > |
| Sat | 02 Mar 1901 | Leigh | 38 | Alverthorpe | 0 | | Mather Lane | | > |
| Sat | 02 Mar 1901 | Liversedge | 3 | Normanton | 2 | | Hightown | | > |
| Sat | 02 Mar 1901 | Manningham | 0 | Castleford | 0 | | Valley Parade | | > |
| Sat | 02 Mar 1901 | Morecambe | 11 | Pontefract | 0 | | Moss Lane | | > |
| Sat | 02 Mar 1901 | Otley | 0 | Oldham | 19 | | Watersheddings | | > |
| Sat | 02 Mar 1901 | Outwood Church | 2 | Holbeck | 5 | | Coach Road | | > |
| Sat | 02 Mar 1901 | Rochdale H. | 3 | Bramley | 7 | | Athletic Ground | | > |
| Sat | 02 Mar 1901 | Runcorn | 18 | Wigan | 0 | | Canal St | | > |
| Sat | 02 Mar 1901 | Stockport | 13 | Shipley | 2 | | Edgeley Park | | > |
| Sat | 02 Mar 1901 | Todmorden | 2 | Sowerby Bridge | 11 | | [unknown] | | > |
| Sat | 02 Mar 1901 | Wakefield T. | 28 | Eastmoor | 6 | | Belle Vue | | > |
| Sat | 02 Mar 1901 | Whitehaven Recs | 0 | Widnes | 3 | | Recreation Gnd | | > |
| Sat | 02 Mar 1901 | Windhill | 3 | Ossett | 5 | | [unknown] | | > |
| Sat | 02 Mar 1901 | York | 10 | Halifax | 2 | | Wigginton Rd | | > |
| Challenge Cup - Round 1 (Rep)
|
|---|
| Wed | 06 Mar 1901 | Barrow | 0 | Brighouse Rangers | 2 | | Cavendish Park | | > |
| Wed | 06 Mar 1901 | Castleford | 21 | Manningham | 2 | | Hunt's Field | | > |
| Wed | 06 Mar 1901 | Maryport | 3 | Lancaster | 0 | | [unknown] | | > |
| Challenge Cup - Round 2
|
|---|
| Sat | 09 Mar 1901 | Aspatria | 2 | Wakefield T. | 21 | | Belle Vue | | > |
| Sat | 09 Mar 1901 | Batley | 6 | Huddersfield | 2 | | Mount Pleasant | | > |
| Sat | 09 Mar 1901 | Bramley | 7 | Oldham | 10 | | Hanson Lane | | > |
| Sat | 09 Mar 1901 | Castleford | 3 | Workington | 2 | | Hunt's Field | | > |
| Sat | 09 Mar 1901 | Dewsbury | 8 | Morecambe | 0 | | Crown Flatt | | > |
| Sat | 09 Mar 1901 | Hebden Bridge | 3 | Broughton R. | 33 | | [unknown] | | > |
| Sat | 09 Mar 1901 | Holbeck | 3 | Bradford | 6 | | Elland Road | | > |
| Sat | 09 Mar 1901 | Keighley | 5 | York | 5 | | Lawkholme Lane | | > |
| Sat | 09 Mar 1901 | Liversedge | 0 | Leeds Parish Church | 5 | | Hightown | | > |
| Sat | 09 Mar 1901 | Maryport | 0 | Hull KR | 11 | | Craven Street | | > |
| Sat | 09 Mar 1901 | Ossett | 5 | Birkenhead | 5 | | [unknown] | | > |
| Sat | 09 Mar 1901 | Runcorn | 16 | Leigh | 4 | | Canal St | | > |
| Sat | 09 Mar 1901 | St Helens | 0 | Stockport | 0 | | Knowsley | | > |
| Sat | 09 Mar 1901 | Sowerby Bridge | 3 | Brighouse Rangers | 6 | | Beech Road | | > |
| Sat | 09 Mar 1901 | Warrington | 19 | Heckmondwike | 2 | | Wilderspool | | > |
| Sat | 09 Mar 1901 | Widnes | 8 | Hunslet | 0 | | Lowerhouse | | > |
| Challenge Cup - Round 2 (Rep)
|
|---|
| Wed | 13 Mar 1901 | Birkenhead | 20 | Ossett | 2 | | Park Station | | > |
| Wed | 13 Mar 1901 | Stockport | 5 | St Helens | 11 | | Edgeley Park | | > |
| Wed | 13 Mar 1901 | York | 12 | Keighley | 0 | | Wigginton Rd | | > |
| Challenge Cup - Round 3
|
|---|
| Sat | 23 Mar 1901 | Birkenhead | 2 | Widnes | 10 | | Park Station | | > |
| Sat | 23 Mar 1901 | Brighouse Rangers | 0 | Hull KR | 7 | | Lane Head | | > |
| Sat | 23 Mar 1901 | Broughton R. | 4 | Oldham | 11 | | Wheater's | | > |
| Sat | 23 Mar 1901 | Dewsbury | 3 | Castleford | 5 | | Crown Flatt | | > |
| Sat | 23 Mar 1901 | Runcorn | 21 | York | 0 | | Canal St | | > |
| Sat | 23 Mar 1901 | St Helens | 5 | Batley | 7 | | Knowsley | | > |
| Sat | 23 Mar 1901 | Wakefield T. | 4 | Bradford | 5 | | Belle Vue | | > |
| Sat | 23 Mar 1901 | Warrington | 11 | Leeds Parish Church | 0 | | Wilderspool | | > |
| Challenge Cup - Round 4
|
|---|
| Sat | 30 Mar 1901 | Batley | 5 | Runcorn | 2 | | Mount Pleasant | | > |
| Sat | 30 Mar 1901 | Hull KR | 5 | Castleford | 5 | | Craven Street | | > |
| Sat | 30 Mar 1901 | Warrington | 10 | Bradford | 8 | | Wilderspool | | > |
| Sat | 30 Mar 1901 | Widnes | 0 | Oldham | 8 | | Lowerhouse | | > |
| Challenge Cup - Round 4 (Rep)
|
|---|
| Wed | 03 Apr 1901 | Castleford | 7 | Hull KR | 2 | | Hunt's Field | | > |
| Challenge Cup - Semi Final
|
|---|
| Sat | 13 Apr 1901 | Batley | 9 | Oldham | 2 | | Fartown | 16,000 | > |
| Sat | 13 Apr 1901 | Warrington | 21 | Castleford | 5 | | Wheater's | 9,000 | > |
| Challenge Cup - Final
|
|---|
| Sat | 27 Apr 1901 | Batley | 6 | Warrington | 0 | | Headingley | 29,563 | > |