Halifax| 5 | | Headingley | | > | | Fri | 24 Feb 1978 | St Helens | 36 | Huyton | 8 | | Knowsley | | > |
| Fri | 24 Feb 1978 | Salford | 9 | Bramley | 7 | | The Willows | | > |
| Sat | 25 Feb 1978 | York | 10 | Warrington | 16 | | Wigginton Rd | | > |
| Sun | 26 Feb 1978 | Blackpool B. | 7 | Huddersfield | 9 | | Borough Park | | > |
| Sun | 26 Feb 1978 | Bradford N. | 21 | Barrow | 13 | | Odsal | | > |
| Sun | 26 Feb 1978 | Dewsbury Celtic | 5 | Wigan | 15 | | Mount Pleasant | | > |
| Sun | 26 Feb 1978 | Dewsbury | 13 | New Hunslet | 22 | | Crown Flatt | | > |
| Sun | 26 Feb 1978 | Hull | 9 | Hull KR | 7 | | Boulevard | | > |
| Sun | 26 Feb 1978 | Leigh | 14 | Featherstone R. | 23 | | Hilton Park | | > |
| Sun | 26 Feb 1978 | Oldham | 21 | Doncaster | 7 | | Watersheddings | | > |
| Sun | 26 Feb 1978 | Pilkington R. | 22 | Castleford | 23 | | Knowsley | | > |
| Sun | 26 Feb 1978 | Swinton | 13 | Batley | 0 | | Station Road | | > |
| Sun | 26 Feb 1978 | Whitehaven | 13 | Wakefield T. | 21 | | Recreation Gnd | | > |
| Sun | 26 Feb 1978 | Widnes | 15 | Rochdale H. | 8 | | Naughton | | > |
| Sun | 26 Feb 1978 | Workington | 16 | Keighley | 5 | | Derwent Park | | > |
| Challenge Cup - Round 2
|
|---|
| Sat | 11 Mar 1978 | Wigan | 10 | Bradford N. | 22 | | Central Park | | > |
| Sun | 12 Mar 1978 | Featherstone R. | 23 | New Hunslet | 7 | | Post Office Road | | > |
| Sun | 12 Mar 1978 | Huddersfield | 13 | Salford | 3 | | Fartown | | > |
| Sun | 12 Mar 1978 | Hull | 8 | Widnes | 20 | | Boulevard | | > |
| Sun | 12 Mar 1978 | Oldham | 11 | St Helens | 26 | | Watersheddings | | > |
| Sun | 12 Mar 1978 | Wakefield T. | 6 | Leeds | 28 | | Belle Vue | | > |
| Sun | 12 Mar 1978 | Warrington | 29 | Swinton | 4 | | Wilderspool | | > |
| Sun | 12 Mar 1978 | Workington | 8 | Castleford | 8 | | Derwent Park | | > |
| Tue | 14 Mar 1978 | Castleford | 8 | Workington | 8 | | Wheldon Road | | > |
| Thu | 16 Mar 1978 | Workington | 13 | Castleford | 20 | | Central Park | | > |
| Challenge Cup - Round 3
|
|---|
| Sun | 19 Mar 1978 | Featherstone R. | 25 | Castleford | 15 | | Post Office Road | | > |
| Sun | 19 Mar 1978 | Leeds | 16 | Bradford N. | 8 | | Headingley | | > |
| Sun | 19 Mar 1978 | St Helens | 31 | Huddersfield | 5 | | Knowsley | | > |
| Sun | 19 Mar 1978 | Warrington | 6 | Widnes | 0 | | Wilderspool | | > |
| Challenge Cup - Semi Final
|
|---|
| Sat | 01 Apr 1978 | Leeds | 14 | Featherstone R. | 9 | | Odsal | 12,824 | > |
| Sat | 08 Apr 1978 | St Helens | 12 | Warrington | 8 | | Central Park | 16,167 | > |
| Challenge Cup - Final
|
|---|
| Sat | 13 May 1978 | Leeds | 14 | St Helens | 12 | | Wembley | 96,000 | > |